QC that keeps up
with your science
See how leading gene therapy teams use QUiCKR to cut turnaround times, reduce NGS spend, and accelerate their path to IND.
Cutting gRNA screening time
from 5 days to 20 minutes
A Stanford-affiliated gene therapy lab needed to screen 48 gRNA candidates per week across multiple nuclease conditions. NGS turnaround was the rate-limiting step — consuming 70% of their QC budget and slowing iteration to once per week.
"We went from waiting a week for NGS results to having indel quantification in hand before lunch. It completely changed how we prioritize gRNA candidates."
— Research Scientist, gene therapy program (Stanford-affiliated lab)AAV titer QC in 1 hour for
process development scale-up
A biotech CDMO running AAV manufacturing for multiple client programs needed rapid in-process controls. Their ddPCR workflow required 4–6 hours and specialized operators. QUiCKR Vector QC gave them same-day QC decisions — without adding instruments or headcount.
"We run three client programs in parallel. QUiCKR let us close the QC loop the same day we manufacture. That kind of feedback loop was impossible with ddPCR."
— Process Development Lead, gene therapy CDMOCatching genomic abnormalities at every
iPSC passage — before they compound
A clinical-stage cell therapy company manufacturing iPSC-derived products needed to monitor chromosomal integrity at each passage during process development. Traditional NGS-based karyotyping took 2–3 weeks per lot, meaning abnormalities were often detected only after multiple downstream passages — too late to course-correct without significant rework.
"We were flying blind between passages. By the time NGS flagged a chromosomal abnormality, we'd already expanded that line three more times. QUiCKR lets us catch issues at the passage they appear — not weeks later."
— Process Development Scientist, clinical-stage iPSC cell therapy companyReady to run QC in minutes,
not weeks?
Book a 30-minute virtual demo. We'll walk through your specific use case and show you what QUiCKR V2 can do for your program.
Book a Demo Download Data SheetQC that keeps up with your science
See how leading gene therapy teams use QUiCKR to cut turnaround times, reduce NGS spend, and accelerate their path to IND.
Cutting gRNA screening time from 5 days to 20 minutes
A Stanford-affiliated gene therapy lab needed to screen 48 gRNA candidates per week across multiple nuclease conditions. NGS turnaround was the rate-limiting step — consuming 70% of their QC budget and slowing iteration to once per week.
Turnaround time
5 days
Samples/week
48
NGS cost/plate
~$2,400
Turnaround time
20 min
Samples/week
1,500+
NGS cost/plate
~$680
“We went from waiting a week for NGS results to having indel quantification in hand before lunch. It completely changed how we prioritize gRNA candidates.”
— Research scientist, gene therapy program (Stanford-affiliated lab)
AAV titer QC in 1 hour for process development scale-up
A biotech CDMO running AAV manufacturing for multiple client programs needed rapid in-process controls. Their ddPCR workflow required 4–6 hours and specialized operators. QUiCKR Vector QC gave them same-day QC decisions — without adding instruments or headcount.
Time to result
4–6 hrs
Hands-on time
~90 min
Samples/run
~20
Time to result
1 hour
Hands-on time
~20 min
Samples/run
150
“We run three client programs in parallel. QUiCKR let us close the QC loop the same day we manufacture. That kind of feedback loop was impossible with ddPCR.”
— Process development lead, gene therapy CDMO
Detecting off-target edits before IND — without the wait
A clinical-stage gene therapy company needed to demonstrate genome stability and detect potential off-target integrations as part of their IND package. Traditional NGS-based genome integrity testing took 3–4 weeks per lot. QUiCKR’s CRISPR kinetics-based platform enabled the same detection with same-day results.
Time per lot
3–4 wks
Cost per lot
~$8,000
Off-target sensitivity
~0.1%
Time per lot
Same day
Cost per lot
~$2,400
Off-target sensitivity
Amp-Seq
Indels (insertions / deletions)
HDR knock-in efficiency
Single nucleotide polymorphisms (SNPs)
Off-target genomic alterations
Allele frequency across cell populations
“Our IND timeline moved up by 6 months. We could iterate on our cell manufacturing process in real time rather than waiting weeks to know if a lot passed QC.”
— VP of process development, clinical-stage gene therapy company
Ready to run QC in minutes, not weeks?
Book a 30-minute virtual demo. We’ll walk through your specific use case and show you what QUiCKR V2 can do for your program.